- Mastriano, 58, made his race about social issues but was weakened by his lack of support from Republicans due to his attendance at the January 6, 2021, riot at the U.S. Capitol.
- Shapiro won 2,985,433 votes, equivalent to 56.3 percent of the vote total, while Mastriano won 2,224,406 votes, or 41.9% of the vote.
- “The results of the 2022 Mid-term Elections are not what we hoped, prayed, and fought so hard for, and yet there is so much for which I am grateful,” Mastriano wrote. “We were massively outspent and yet we outperformed Republican gubernatorial candidates that benefitted from millions of dollars and the support of national PACs and organizations we did not.”