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Federal Fentanyl Crackdown Drops Overdose Deaths To Record Low

As fentanyl overdose deaths fall to levels not seen since 2019, Republicans in both the executive and legislative branches say they intend to push those numbers even lower.

State-level data reinforces the trend. In Pennsylvania, a state with a higher average rate of overdose deaths than most states, overdose deaths dropped by 60% in 2025, a decline Republicans attribute to President Donald Trump’s aggressive counter-narcotics enforcement.

Executive Moves

U.S. Customs and Border Protection recently announced that in 2026 alone, agents along the southwest border have seized enough fentanyl to kill more than 100 million Americans—despite having worked without pay for 76 days.

The seizures follow a series of actions by the Trump administration to escalate its response to the crisis. The president designated drug cartels as Foreign Terrorist Organizations and classified fentanyl and its precursor chemicals as weapons of mass destruction.

Those designations expanded federal authority to target the manufacture and distribution of fentanyl, which officials say is largely controlled by organized criminal networks and poses a growing national security threat.

“As President of the United States, my highest duty is the defense of the country and its citizens,” Trump wrote at the time. “Accordingly, I hereby designate illicit fentanyl and its core precursor chemicals as Weapons of Mass Destruction.”

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